8 Best Huperzine A Supplements (2024) Reviewed and Compared

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If you’re looking for a supplement that will naturally give you a brain boost and increase your productivity levels, huperzine A might be perfect for you. Huperzine A supplements have been gaining popularity as a natural way to keep your memory sharp and your mind young.

In fact, you’ll find Huperzine A is many of the most popular “nootropic” supplements.

However, most of the claims surrounding huperzine A are based on a small pool of research.

So is it really worth the hype? We dive into the potential benefits of huperzine A and the best huperzine A supplements on the market.

What Is Huperzine A?

Warning, we’re about to get a little technical.

Huperzine A is a dietary supplement derived from Chinese club moss plants, formally known as Huperzia serrata. It operates as a reversible Acetylcholinesterase inhibitor, meaning it prevents enzymes from breaking down the neurotransmitter acetylcholine in the body.

Since acetylcholine plays such a large role in memory, learning, and cognitive processing, increased levels of acetylcholine are expected to improve brain health. In other words, taking a huperzine A supplement might increase your acetylcholine levels and therefore enhance your brain function.

Right now, huperzine A is being studied primarily for its potential to treat diseases associated with memory. For example, it’s currently in preliminary trials for Alzheimer’s disease prevention.

However, huperzine A has also been gaining popularity in the wellness world as a general nootropic. It’s claimed to enhance memory, increase productivity, improve concentration, and even promote creativity for general consumers.

However, it’s unclear whether huperzine A can actually improve cognitive function for healthy individuals. Our next section explores what research has to say about these claims.

Why Should You Take a Huperzine A Supplement?

Research on the benefits of huperzine A has been primarily focused on its ability to prevent and treat diseases associated with memory. Studies indicate that the plant might be a useful preventative tool and supplementary treatment for memory-related conditions like Alzheimer’s Disease.

For example, a 2013 animal study found that huperzine A caused an enhancement of cell growth in the hippocampus region of mice, which plays a large role in learning and memory. This suggests that huperzine A can be a preventative tool for aging-related cell degeneration. Another study discovered that huperzine A might help treat Alzheimer’s disease by reducing iron accumulation in the brain and slowing down the rate at which neurons die.

While research on huperzine A’s ability to treat age-related neurological conditions is promising, to say that it can enhance memory and boost productivity in the average Joe is a stretch, to say the least. I’m not saying it’s impossible, but more research is definitely needed to further back those claims.

That being said, huperzine A is a safe supplement with no serious side effects in healthy individuals. If you’re looking for a supplement that improves brain function, there’s no harm in trying it.

Another Reason to Supplement with Hup A: It Costs Less Than a Nootropic

Nootropics usually contains a handful of ingredients designed to improve you focus, energy, and boost your productivity. The base ingredients themselves aren’t expensive, yet these products wind up costing a lot. A more economical approach is to choose the ingredients with the benefits you’re going for, and buy those. 

The 8 Best Huperzine A Supplements

Now let’s check out the best huperzine A supplements on the market. Every product on our list is third-party tested. 

*Disclaimer: We do have affiliate links throughout this article, which means we receive a commission if you purchase from any of our links. This supports our mission to bring complicated health and fitness info in an entertaining package. And it keeps us from putting up annoying things like banner ads. Those suck.

1) Double Woods Huperzine A

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Price: From $19.95

Overall, Double Woods Huperzine A is a great, simple product. Its high-quality ingredients are GMP-certified and third-party tested. The only active ingredient it contains is 200 mcg of huperzine A, so you’re getting just what you need in every serving.

Double Woods supplements are made and tested in the USA. They also offer a money-back guarantee on all purchases, which shows they believe in their product and have their customer’s best interests in mind.

2) California Gold Nutrition Huperzine A

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Price: From $35

California Gold Nutrition’s product is perfect for people who are already used to taking huperzine A, as it has a higher dosage than our other picks on this list. Its third-party tested ingredients are non-GMO, gluten-free, and soy free. They also come in a vegetarian capsule, making them suitable for any diet.

Each bottle has 90 350 mcg capsules.

3) Source Naturals Huperzine A

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Price: From $25.19

Source Naturals Huperzine A is another option that checks off all of our “what we want in a supplement” boxes. Its high-quality ingredients are third-party tested and free of gluten, soy, wheat, sugar, artificial colors, and artificial flavors. Its dosing makes it a great option for people who are new to taking huperzine A. Each bottle contains 100 200 mcg tablets.

4) Bulk Supplements Huperzine A Powder

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Price: From $29.96

If capsules aren’t your thing, Bulk Supplements Huperzine-A Powder is the perfect option for you. It can be added to any drink and is free of sugar, soy, dairy, and gluten, making it suitable for a variety of diets.

It is also more affordable than the softgels and capsules on our list. Just one of these packages contains over 650 150 mcg servings, so you definitely get your money’s worth. Plus, it has an air-tight, resealable top for long-term use and can be shipped for free to the contiguous United States.

5) Life Extension Huperzine A

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Price: From $30.00

Life Extension is another great option, offering 200 mcg of huperzine A in every serving. Its high-quality ingredients are third-party tested and GMP-certified. Plus, its huperzine A supplement comes in a vegetarian capsule and is gluten-free, making it suitable for a range of diets. The only downside is that this bottle contains only 60 huperzine A capsules, which is less than the other options on our list.

6) Pure Nootropics Huperzine A

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Price: From $14.99

Pure Nootropics Huperzine A is another credible, high-quality product on our list. It is third-party tested, and you can even see certificates of analysis on Pure Nootropic’s website, which gives them bonus points for credibility. They also offer a 30-day money-back guarantee, which shows they’re confident in their product.

Every 200 mcg of huperzine A comes in a veggie capsule, and each bottle contains 90 servings.

7) Nutricost Huperzine A

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Price: From $26.95

Nutricost Huperzine-A is another product that offers both quality and quantity. Its capsules are non-GMO, soy-free, and gluten-free. Plus, it is GMP compliant and third-party tested in a facility registered with the food and drug administration.

Each bottle contains 240 200 mcg servings, which is about an eight month supply. Not too shabby if you ask me.

8) Naturebell Huperzine A

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Price: From $19.95

Naturebell Huperzine A is a good product for hupA newbies and vets alike. It’s advertised as 400 mcg per serving because Naturebell recommends taking two per day. However, if you’re new to taking huperzine A, you can take one capsule a day for a six month supply.

Its ingredients are third-party lab tested for purity and quality. They’re also non-GMO, gluten-free, soy-free, and free of any additives.

How We Ranked

Although we ranked these supplements, we want you to decide on the best product for you. Here’s what we took into consideration when ranking these products.

Strict Testing Standards

The FDA doesn’t regulate the supplement industry. That’s why we only select companies that adhere to Good Manufacturing Practice (GMP) regulations and have their products third-party tested.


Health experts recommend taking huperzine A in doses of 100 to 400 mcg, with beginners starting on the lower end and increasing their dosages as they adjust to the nootropic. Because of this recommendation, we looked for products in the 100- 400 mcg range.


Let’s be honest, there are a lot of bogus, overpriced supplements out there. And we’re all about getting the best bang for your buck. That’s why we select products with great value and fair prices.

Frequently Asked Questions

Is it safe to take huperzine A?

Huperzine A is safe for most people. However, it can slow the heart rate. If you have a pre-existing heart condition, you should talk to a healthcare professional before using huperzine A.

Does huperzine A have side effects?

Huperzine A can cause mild side effects including dry mouth, blurred vision, constipation, vomiting, and diarrhea.

Is it okay to take huperzine A every day?

Huperzine A is safe for daily use. Most companies selling huperzine A supplements recommend taking 100 to 200 mcg every day. However, the effects of huperzine A are still being studied. You should speak with a healthcare professional before trying this supplement.

About the Author

Kelly is a Hawaii-based wellness writer. She graduated with her Master's degree in English and combines her background in health care, wellness, and fitness with her writing background to create content for various health-related companies. In her free time, you'll find her reading on the beach or training for her next half marathon.

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