4 Best Lumbrokinase Supplements: Top Picks for 2024

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Lumbrokinase supplements have been gaining popularity in recent years for their potential health benefits, in particular digestion support. Derived from the enzyme found in earthworms, these supplements are believed to support healthy blood circulation and assist in breaking down fibrin, a protein that can cause blood clots. Many people are turning to lumbrokinase supplements as a natural way to maintain good cardiovascular health and overall well-being.

However, not all lumbrokinase supplements are created equal. The key to finding the best lumbrokinase supplement lies in understanding the potency and quality measures. The amount of active lumbrokinase enzyme present in each supplement varies, so it’s crucial to consider potency when selecting a supplement.

Another essential factor in choosing a high-quality lumbrokinase supplement is the manufacturing and purity standards.

Look for supplements produced in facilities that abide by strict quality controls and obtain third-party testing to ensure that they contain what they claim and are free of contaminants. It’s also wise to look for products with minimal additives and fillers to ensure maximum efficacy and safety.

We’ve dedicated our time and efforts to researching and testing different lumbrokinase supplements, focusing on their potency, quality, and overall effectiveness, to bring you a comprehensive guide to finding the best option for your needs. 

Best Lumbrokinase Supplements of 2024

Note: We have affiliate links throughout this article, which means we receive a commission if you purchase from any of our links. This isn’t your first time on the internet, so you likely already knew this.

We’ve researched and compiled a list of the top lumbrokinase supplements for you to consider. These products have been selected for their quality, effectiveness, and overall customer satisfaction.

1) Etta Vita Lumbrokinase Enzymes

Etta Vita Lumbrokinase Enzymes Supplement

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For those seeking cardiovascular support, detoxing and enhanced gut health, try Etta Vita’s Potent Lumbrokinase Supplement.


  • Powerful formula with 800,000 LKU per capsule (most potent)
  • Slow Release Capsules
  • Supports blood flow and digestion
  • Community-focused brand


  • None

Etta Vita’s Potent Lumbrokinase Supplement is crafted to provide cardiovascular support, digestion enhancement, and gut health improvement. It brings more than 30 times of potency than nattokinase, offering an excellent choice for those focusing on blood flow and detoxing. Simply, it’s the most potent product on our list.

With its powerful formula of 40mg per serving and 800,000 LKU per capsule, this lumbrokinase supplement ensures optimal fibrinolytic activity while supporting your overall health.

Its enzymes aid in breaking down biofilms, preventing blood clots, and ensuring optimal digestion. One thing to consider, though, it may be difficult to gauge the supplement’s effectiveness without long-term use.

What we truly appreciate about Etta Vita is not only the quality of their supplements but also their commitment to giving back to the community. They have proudly partnered with organizations such as Feed The Hungry and Vitamin Angels in the fight against malnutrition across the globe.

In conclusion, Etta Vita’s Potent Lumbrokinase Supplement is a powerful supplement that supports cardiovascular health, digestion, and gut well-being. Although measuring effectiveness might be a challenge and there’s no return option, we, as users, believe it provides a valuable option for those in need of such support.

2) Double Wood Supplements LumbrokinaseDouble Wood Lumbrokinase Enzymes Supplement

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If you’re searching for a lumbrokinase supplement that’s high in quality and has proven results, Double Wood’s Lumbrokinase Enzymes Supplement is the perfect choice for you.


  • Supports healthy circulation and overall function
  • Two-month supply per bottle
  • No fillers, Gluten-free, and Non-GMO
  • 60 Monday-Back Guarantee


  • None

Double Wood Supplements is one of the most reputable, high-quality brands out there. They specialize is single-ingredient supplements like this so you can create your custom stack.

Each bottle comes with a two-month supply of 120 capsules, making it one of the more cost-effective options on the market. We appreciate that Double Wood’s lumbrokinase supplement is manufactured and tested in the USA, ensuring quality and safety. Furthermore, the fact that it’s gluten-free and contains no fillers is a huge plus for us.

However, we must mention that this supplement does require a daily commitment to see the best results. Also, some users have reported that it cannot be mixed with other supplements without causing an adverse reaction. This may limit your options if you’re looking to combine it with other health remedies.

In conclusion, Double Wood’s Lumbrokinase Enzymes Supplement is an excellent choice if you’re seeking a high-quality product that delivers results in supporting healthy circulation and overall function. Just be prepared to commit to daily use and keep in mind that you might not be able to mix it with other supplements.

3) Doctor’s Best Lumbrokinase Supplement

Doctor's Best Lumbrokinase Cardiovascular Support

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We think this is a great pick for those seeking a highly effective lumbrokinase supplement with a good reputation and supportive user experiences.


  • Highly active enzyme for cardiovascular support
  • Derived from a unique, stable group of fibrinolytic enzymes
  • Formulated for optimal absorption in the intestinal tract


  • Possible stomach upset if taken with other enzymes
  • A bit pricy

Doctor’s Best Lumbrokinase has quickly become our go-to supplement for supporting and maintaining healthy cardiovascular function. The unique enzymes derived from the earthworm Lumbricus rubellus provide a highly active form that has been well-studied and utilized in China for years. Taking this supplement feels like a gentle yet effective way to ensure our cardiovascular health is on track.

We appreciate that these vegetarian capsules have been designed for optimal absorption in the intestinal tract. This ensures we’re getting the most out of our lumbrokinase, helping to maintain healthier blood and lower blood viscosity, as backed by clinical studies. We’ve tried other brands, but none have quite matched up to Doctor’s Best formulation.

One thing to note is that Lumbrokinase should be taken on an empty stomach to avoid any potential stomach upset. We’ve learned that taking it with other enzymes, such as Nattokinase or Serrapeptase, may cause discomfort, so it’s important to follow the directions for use. Some users also report that it takes time before noticeable effects are felt, which is typical of most natural supplements.

In conclusion, with its powerful enzyme formula, ease of absorption, and supportive research, we feel confident recommending Doctor’s Best Lumbrokinase Cardiovascular Support to anyone looking to improve their cardiovascular health.

4) Mr. Mercola Lumbrokinase Enzymes Delayed Release

Dr. Mercola Lumbrokinase Enzymes

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We highly recommend Dr. Mercola Lumbrokinase Enzymes for those seeking a quality supplement to support cardiovascular and cognitive health.


  • Effective blend of fibrinolytic enzymes and protease
  • Supports healthy inflammatory response and circulation
  • High-quality, GMO-free ingredients
  • Delayed Release


  • Some confusion regarding listed enzyme amounts
  • Possible mild side effects
  • Pricy

We tried Dr. Mercola Lumbrokinase Enzymes and were impressed with the blend of fibrinolytic enzymes and protease, which help break down unwanted proteins in the body. This formula supports a healthy inflammatory response, circulation, and balanced energy levels. Since these capsules have a delayed release, the contents reach our intestines for proper digestion and absorption.

However, there has been some confusion among customers regarding the label’s content. Some customers report receiving bottles listing 11mg of enzymes per serving rather than the 40mg stated on the product image. The seller may need to clarify this discrepancy for customer satisfaction.

We noticed that some users experienced minor side effects such as nausea and lightheadedness after taking this supplement. It is essential to consult with a healthcare professional before starting any new supplement, especially if you are sensitive to new products.

Lastly, we found that the price for Dr. Mercola Lumbrokinase Enzymes can be a bit steep, especially for international customers who need to pay additional customs fees. Despite the cost, the overall quality and effectiveness of this supplement make it worth considering for those seeking a boost in cardiovascular and cognitive health.

Buying Guide

When searching for the best lumbrokinase supplement, it’s essential to keep a few factors in mind to ensure we’re choosing the right product for our needs. In this buying guide, we’ll discuss the key features to consider and some tips to make our selection process easier.

First of all, we should pay close attention to the dosage. Different products might contain varying amounts of lumbrokinase. To receive the desired benefits, it’s crucial to opt for a supplement with an appropriate dosage according to our specific needs. It’s always best to consult with a healthcare professional to determine the optimum dosage.

Next, let’s consider the supplement’s purity and quality. We want to make sure that the product we choose is made with high-quality ingredients and doesn’t contain any harmful additives or fillers. A good way to ensure this is by looking for certifications or third-party lab testing results. These details can often be found on the product’s label or the manufacturer’s website.

While exploring various supplements, we should also pay attention to their format. Lumbrokinase supplements can come in different forms, such as capsules, tablets, or softgels. Each of these forms can have its own set of advantages and disadvantages, so we should choose the one that feels the most convenient and compatible with our lifestyle.

Don’t forget to consider the supplement’s cost-effectiveness. We want a product that offers value for money through the potency and quality it provides. Comparing different products’ prices and ingredients can help us make an informed decision and find the best fit within our budget.

Finally, always check for customer reviews and feedback. They can provide essential insights into the product’s performance and effectiveness and help us avoid potential pitfalls. When browsing reviews, it’s essential to keep an open mind and consider multiple sources to form a well-rounded opinion.

Why only 4 options?

Well, the truth is, there aren’t a lot of great products from reputable brands out there. That’s why we kept our list short, with only brands we trust.

In summary, when searching for the best lumbrokinase supplement, we should consider:

  • Dosage
  • Purity and quality
  • Format (capsules, tablets, softgels)
  • Cost-effectiveness
  • Customer reviews and feedback

By keeping these factors in mind, we can confidently select the ideal lumbrokinase supplement for our needs.

Frequently Asked Questions

What are the benefits of using a lumbrokinase supplement?

Lumbrokinase supplements offer various health benefits. Primarily, they help with the break down of fibrin in the body, leading to improved blood circulation and reducing the risk of blood clots. Additionally, lumbrokinase can support cardiovascular health and may help the body naturally dissolve biofilms that contribute to various health issues.

How does lumbrokinase compare to serrapeptase and nattokinase?

Lumbrokinase, serrapeptase, and nattokinase are all enzyme supplements that assist with breaking down fibrin and promoting healthy blood flow. Each enzyme has its unique properties. Lumbrokinase is derived from earthworms and is known for its potent fibrinolytic properties. Serrapeptase comes from the silkworm, focusing more on breaking down non-living tissue and reducing inflammation. Nattokinase, sourced from fermented soybeans, supports blood clot breakdown and overall cardiovascular health.

Are there any side effects of taking a lumbrokinase supplement?

Lumbrokinase supplements are generally safe when taken as directed. However, some individuals may experience mild side effects such as abdominal bloating, diarrhea, and nausea. As with any supplement, we suggest consulting your healthcare professional if you are pregnant, nursing, taking blood-thinning medications, or have a pre-existing medical condition before using lumbrokinase.

What’s the optimal dose of lumbrokinase?

The optimal dosage of lumbrokinase varies depending on the individual’s needs and the specific supplement formulation. Generally, a daily dose of 30-50mg of lumbrokinase is recommended for most adults. It’s best to follow the manufacturer’s guidelines and consult with a healthcare professional to find the appropriate dosage for you.

How does lumbrokinase help with biofilm?

Biofilms are a protective matrix produced by certain bacteria, making them more resistant to antibiotics and the immune system. Lumbrokinase can help break down the extracellular components of biofilms, allowing the immune system and other treatments to more effectively target the bacteria within. This can aid in the management of chronic infections associated with biofilms.

What is the source of lumbrokinase in supplements?

Lumbrokinase is a group of enzymes sourced from the Lumbricus rubellus species of earthworm. These enzymes have potent fibrinolytic properties, making them beneficial for supplements supporting cardiovascular health and blood flow.

How quickly does lumbrokinase work?

The effects of lumbrokinase can vary among individuals and depend on factors such as dosage, lifestyle, and overall health. Some people may notice improvements within days of starting the supplement, while others may need a few weeks to observe the benefits. As with any supplement, it’s essential to give lumbrokinase time to work and monitor your progress with a healthcare professional.

About the Author

David William Rosales is a writer and strength coach. He's the head trainer and editor at Roman Fitness Systems. In addition to helping run RFS, he's also the head editor for, the official website of the Strength and Conditioning Association of Professional Hockey. You can also check out his Instagram, he's pretty easy on the eyes.

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