11 Best Quercetin Supplements (2022) Reviewed and Compared
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Posted by
David Rosales
Quercetin has become one of the most popular supplements for overall health and longevity. Today we’re looking at the best quercetin supplements on the market.
What is Quercetin?
Quercetin is a bioflavonoid, antioxidant, anti-inflammatory and some other terms that make it sound healthy.
It’s found in many fruits, vegetables, and wine. It’s especially abundant in blueberries, capers, onions, apples, and more. In fact, here’s a nice little chart from this study on quercetin.
Basically, it’s a thing in healthy foods that’s partially responsible for what makes them healthy.
Quercetin has been looked at for more than just its antioxidant properties. More recently, there’s been a lot of talk and emerging research on its roles as an anti-aging supplement, albeit one that’s different from other anti-aging supplements like NMN and berberine.
(And if you’re looking for anti-aging supplements, you can also check out our guides on the best NMN supplements and the best berberine supplements.)
What to Look For in a Quercetin Supplement
The research on quercetin is quite extensive. However, it doesn’t demonstrate show-stopping benefits in all cases. Specifially, there’s a big difference in the effects of quercetin studies that were cell-cultured studies versus living studies.
It’s sad, but the cell studies often show amazing results, but they don’t carry over to humans or other animals. One of the main reasons for this is that regular quercetin has low oral bioavailability.
If quercetin could magically appear in your bloodstream, it would be super effective for all the advertised benefits.
The Best Quercetin Supplements All Focus on Improving Bioavailability
If a supplement doesn’t recognize the difference in cell versus living studies, and plans accordingly by boosting the supplement with something like a liposomal compound, which can act as a shield for the quercetin, then it won’t be as effective.
Without further ado, then here are the best quercetin supplements on the market right now.
*Note: We do have affiliate links throughout this article, which means we receive a commission if you purchase from any of our links. This supports our mission to bring complicated health and fitness info in an entertaining package. And it keeps us from putting up annoying things like banner ads. Those suck.
1) Renue by Science LIPO Quercetin
Renue by Science consistently leads the charge with some of the best longevity and anti-aging products on the market, and their quercetin product is no exception.
The first aspect that makes Renue’s product our top pick is it contains a liposomal capsule that protects the quercetin during digestion and increases its bioavailability. As we mentioned, if a supplement gets destroyed in the stomach, it doesn’t make it to your bloodstream, and you won’t get any of the effects.
A June 2021 study even found a 20-fold increase in absorption when using a liposomal quercetin compared to an ordinary quercetin.
Read that again. 20 times increase. Even if that’s higher than what you’d see in reality, it’s still a massive difference.
Second, Renue has some of the strictest and cleanest testing policies. Every batch is GMP-certified AND made in an FDA-approved facility.
Every batch is third-party tested, and they display their purity results.
Each bottle contains 90, 150mg capsules. The dose is lower than some products. But remember, they’re focused on absorption.
And we’re such big fans of Renue that we’ve teamed up with them to give you 10% off all of their products (automatically applied when you use our link.)
2) Thorne ResveraCel
A lot of the research on quercetin has shown that it has a synergistic effect when combined with resveratrol, which was the conclusion of this popular 2015 study. This means that when taken together, both of their positive effects improve.
And, resveratrol in its own right has a lot of interesting research for anti-aging, longevity, and overall health.
This product from Throne derives its strength because it’s a combination of quercetin and resveratrol. Each capsule contains 125mg of quercetin and 75mg of resveratrol. This is lower than a clinically effective dose, so you might want to take more one capsule for the maximum effect.
It also contains over 200mg of NR (nicotinamide ribose), which is a precursor to NAD. We’ve talked about this in-depth in our article on another NAD precursor, NMN.
Thorne is also a third-party-tested, GMP-approved company with a great reputation.
While the cocktail of anti-aging ingredients is impressive, Thorne’s product isn’t liposomal, so there are concerns about the bioavailability and absorption.
3) Thorne Quercetin Phytosome
Another product from Thorne contains a form of quercetin called quercetin phytosome. Phytosomes, like liposomes, are a lipid membrane. It’s a different kind of lipid membrane, but it’s the same idea with the goal of improving the bioavailability of quercetin.
A 2019 study, showed that quercetin bioavailability for quercetin phytosome was higher compared to regular quercetin dihydrate (the typical form).
Again, Thorne only makes high-quality products, so this product should also make your shortlist of options.
4) Quicksilver Scientific Hista-Aid
Another benefit of quercetin supplements is their anti-allergy benefits, which Quicksilver Scientific places at the forefront of their quercetin product. They have other ingredients that can support allergies and the immune system as well: luteolin, diindolylmethane, and vitamin C, in addition to quercetin.
The dose is smaller, with only 16mg of quercetin per serving (four sprays). But it’s a liposomal product, so it has better bioavailability.
Quicksilver also is GMP-certified, and makes only high-quality products.
5) Double Wood Supplements Quercetin with Bromelain
In terms of a combination of value, quality, and a high dose, Double Wood’s quercetin product contains 600mg per capsule. It also contains 100mg of bromelain, an additional immune support ingredient. With 120 capsules for under $23, it’s also a phenomenal value.
Double Wood even goes beyond the GMP certification. They display their certificate of analysis for purity front and center on their website.
6) NOW Foods Quercetin with Bromelain
If you’re looking for a solid, quality, inexpensive, and simple product, NOW Foods quercetin is a great option. Each capsule contains 400mg of quercetin. It also has bromelain, which is an herb that can support the immune system.
For just $18 a bottle, from a trusted, GMP-certified brand, this is a solid quercetin supplement choice.
7) Bluebonnet Nutrition Super Quercetin
Bluebonnet Nutrition’s Super Quercetin contains 250mg per capsule, along with bromelain, rose hips, a citrus bioflavonoid complex, and more. Competitively priced, this is a great quercetin supplement with extra immune system boosts.
8) Thorne Quercenase
Yes, Thorne has another Quercetin product that deserves our consideration. It’s the same as their quercetin phytosome product, except it also contains 100mg of bromelain. As mentioned, this is also an immune-boosting ingredient.
But it’s $10 more per bottle just for the bromelain, so I would go for their simple quercetin phytosome product.
9) Solgar Quercetin Complex
Solgar’s Quercetin Complex similarly contains an array of immune-boosting ingredients. You can purchase 50 capsules with 250mg of quercetin for just $12.58 at iherb, making it one of the best deals for capsules.
10) Jarrow’s Formula Quercetin
This simple product from Jarrow has the benefit of a high dose. Each capsule contains 500mg of quercetin, the highest on our list, at a reasonable price. If you want to take higher doses, which is what most studies use, look into this option.
BONUS: Pure Bulk Quercetin (Best Bulk Option)
As a bonus, we wanted to highlight the best buy-in-bulk option on the internet. You can buy it in capsules or powder, but the powder is even less expensive. They have various sizes, but their starting point of 25 grams for $15 is already a better deal than any other products on the list on a cost per gram basis.
However, it’s an unflavored powder, so make sure you mix it in a smoothie or something.
How We Ranked
Here are the factors that went into our decision-making process.
Delivery Mechanism
As we’ve mentioned, regular quercetin has poor bioavailability. This means with ordinary quercetin supplements, you’re not actually absorbing the quercetin. That’s why our top products often have liposomal or phytosomal delivery mechanisms. These are when the quercetin is embedded in phospholipid molecules, acting as a protective barrier, like the walls of a castle. Of the two, we’ve seen more convincing research on liposomal delivery, in particular.
Product and Company Quality
We only included companies on our list that are third-party, GMP certified. However even with this, companies can skimp out on strict quality standards. That’s why we also gave a nudge to companies that go above and beyond, by manufacturing in an FDA-approved facility and displaying the purity results of each batch.
Cost and Value
This is a simple one. All else being equal, it makes sense to buy the less expensive product. We factored in the cost per gram into this as well.
Synergistic Ingredients
As we talked about with Thorne’s ResveraCel, quercetin in particular has synergistic benefits with resveratrol. Other products include other immune-boosting ingredients as well. We factored the impact of these other ingredients into our list.
FAQ
Here are some of your common questions about quercetin answered.
What is a flavonoid and what makes quercetin one?
Flavonoid is just one of those words we pretend to know what it means, right? They’re a classification of compounds found in fruits and vegetables. They’re grouped together because of their antioxidant properties.
How can quercetin help us live longer?
The mechanism is complex, but the concept is simple. Basically, as we age, our body builds up senescent cells. These are cells that have run amok. They start misbehaving and bullying other cells. They’re kind of like that kid in high school who used to be cool, but then went off the rails and just became a total cancer in the classroom. Wow, I’m really mixing analogies here.
The point is, quercetin can clear out senescent cells. This has been shown in several studies, including this December 2021 paper in Nature.
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